Thyroxine binding by serum proteins
نویسندگان
چکیده
منابع مشابه
Thyroxine-binding by Serum
The occurrence of hypercholesterolemia, lowered basal metabolic rate and depressed serum proteinbound iodine in the nephrotic syndrome has directed attention to the thyroid gland in this disorder. Although hypothyroidism has been suspected, these patients are usually considered, on clinical grounds, to be euthyroid, and they fail to respond in a specific manner to even large doses of thyroid ho...
متن کاملThyroxine Binding by Human Serum Albumin*
Thyroxine and triiodothyronine are transported in the blood as noncovalent complexes with certain serum proteins. This has been shown by many investigators and was the subject of an extensive recent review by Robbins and Rall (1). The binding proteins are an a-globulin (called thyroxine-binding globulin), a prealbumin, and serum albumin. The first appears to be the most significant binder of th...
متن کاملThyroxine binding by human serum albumin.
Thyroxine and triiodothyronine are transported in the blood as noncovalent complexes with certain serum proteins. This has been shown by many investigators and was the subject of an extensive recent review by Robbins and Rall (1). The binding proteins are an a-globulin (called thyroxine-binding globulin), a prealbumin, and serum albumin. The first appears to be the most significant binder of th...
متن کاملBinding of Thyroxine by Human Serum Albumin
In previous work from this laboratory (1) studies on equilibrium dialysis were carried out to determine the binding constants for the interaction of human serum albumin with thyroxine and its analogs. The classical technique of equilibrium dialysis as described by Scatchard and others (2-6) was employed. At present it seems clear that thyroxine in human serum migrates to at least three differen...
متن کاملRapid determination of thyroxine binding proteins of human serum.
A simple method is described for determing thyroxine binding proteins in human serum by electrophoresis at pH 8.6, using cellulose acetate membrane as the supporting medium. The procedure had high reliability in sera of normal subjects, pregnant women and patients with decreased thyroxine binding capacity of thyroxine binding globulin.
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1960
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1960.sp006527